Precision and reproducibility of semi-automated late gadolinium enhancement quantification techniques in patients with hypertrophic cardiomyopathy
نویسندگان
چکیده
Background The presence and extent of hyper-enhancement (HE) on Late Gadolinium Enhancement (LGE) has been associated with adverse events in patients with Hypertrophic Cardiomyopathy (HCM). Signal-threshold techniques are routinely employed for quantification; however, the precision and reproducibility of these versus a gold standard remains uncertain. Full Width Half of Maximum (FWHM) techniques are suggested to provide greater reproducibility than Signal Threshold versus Reference Mean (STRM) techniques, however the precision of these approaches versus manual assignment of optimal signal intensity(SI) thresholds has not been studied. We compare all known semiautomated LGE-quantification techniques for precision and reproducibility among patients with HCM.
منابع مشابه
Accuracy and reproducibility of semi-automated late gadolinium enhancement quantification techniques in patients with hypertrophic cardiomyopathy
BACKGROUND The presence and extent of late gadolinium enhancement (LGE) has been associated with adverse events in patients with hypertrophic cardiomyopathy (HCM). Signal intensity (SI) threshold techniques are routinely employed for quantification; Full-Width at Half-Maximum (FWHM) techniques are suggested to provide greater reproducibility than Signal Threshold versus Reference Mean (STRM) te...
متن کاملMyocardial fibrosis delineation in late gadolinium enhancement images of Hypertrophic Cardiomyopathy patients using deep learning methods
Introduction: Accurate delineation of myocardial fibrosis in Late Gadolinium Enhancement on Cardiac Magnetic Resonance (LGE-CMR) has a crucial role in the assessment and risk stratification of HCM patients. As this is time-consuming and requires expertise, automation can be essential in accelerating this process. This study aims to use Unet-based deep learning methods to automate the mentioned ...
متن کاملComparison of Semi-automated Late Gadolinium Enhancement Quantification Techniques in Measuring Septal Fibrosis in Patients with Dilated Non-Ischemic Cardiomyopathy
Background Mid-wall striae pattern late gadolinium enhancement (LGE) has been shown to independently predict future outcomes in patients with dilated non-ischemic cardiomyopathy (NICM). Standardized quantification tools are of particular interest for clinical translation of this novel imaging marker. However, signal intensity (SI) based threshold techniques, such as Signal Threshold versus Refe...
متن کاملThe extent of late gadolinium enhancement can be assessed fast and reproducible using semi-quantitative method in patients with hypertrophic cardiomyopathy
Background In hypertrophic cardiomyopathy (HCM) assessment of late gadolinium enhancement (LGE) is increasingly important as LGE has been demonstrated to be an adverse prognosticator. Manual delineation of LGE after visual assessment is labour-intensive. Automatic quantification is limited by its dependence on signal/noise ratio and varying definition of LGE. Our aim is to assess inter-individu...
متن کاملSegmental late gadolinium enhancement and gadolinium extracellular volume in hypertrophic cardiomyopathy
Background Late gadolinium enhancement (LGE) by cardiac magnetic resonance (CMR) is a common finding in patients with hypertrophic cardiomyopathy (HCM), and its extent correlates with clinical parameters such as ventricular tachycardia and sudden cardiac death. While LGE has been shown to reflect focal replacement fibrosis, recently optimized T1 mapping techniques have allowed for the quantific...
متن کامل